The Senate has passed a nearly $1.5 trillion Republican tax bill that’s historic in scope and an urgent political priority for President Donald Trump and the GOP.

The vote was 51-49, largely along party lines. Not a single Democrat voted in favor of the legislation, including Democratic Sen. Joe Donnelly, who issued the following statement:

“From the beginning I’ve been willing to partner with Republicans, with Democrats, with the president, with this Administration. I agreed with President Trump’s stated goals of supporting the middle class and keeping jobs here in America…Here’s the bottom line: I opposed Mitch McConnell’s bill because it is not tax reform, it’s a partisan tax hike on Indiana’s middle class, it does nothing to prevent outsourcing of US jobs to foreign countries, and it’s a giveaway to Wall Street and other big money interests.”

The bill would bring the first major overhaul of the U.S. tax system in three decades. It was supported by Republican Sen. Todd Young, who issued the following statement:

“This is a big win for Hoosiers. Not only did we repeal the oppressive individual mandate tax of Obamacare, but we acted on tax reform for the first time in 30 years that will ensure Hoosiers have a code that is fairer, that is simpler, and that allows them to keep more of what they earn. Repealing the Obamacare tax, doubling the standard deduction, doubling the Child Tax Credit, and lowering rates for middle-income Americans will provide needed relief.”

The measure must be reconciled with a version the House passed last month.

The Associated Press contributed to this story.